Anti-KLF4, clone [4G6E11]

Anti-KLF4, clone [4G6E11]
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
200-301-CF0 100 µg - -

6 - 10 Werktage*

698,00 €
 
Anti-KLF4 Monoclonal Antibody was affinity purified from monospecific antiserum by immunoaffinity... mehr
Produktinformationen "Anti-KLF4, clone [4G6E11]"
Anti-KLF4 Monoclonal Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least three isoforms of KLF4 are known to exist, this antibody will detect all three. KLF4 antibody will not cross-react with other Kruppel-like family members. KLF4 is a transcription factor that functions as both a transcriptional activator and repressor to regulate proliferation and differentiation of multiple cell types. The role of KLF4 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing KLF4 and the transcription factors POU5F1, Sox2, and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing KLF4, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine. KLF4 interacts directly with POU5F1 and Sox2 in iPS and ES cells and activates the target gene NANOG.
Schlagworte: Anti-EZF, Anti-KLF4, Anti-Krueppel-like factor 4, Anti-Gut-enriched krueppel-like factor, Anti-Epithelial zinc finger protein EZF
Hersteller: Rockland Immunochemicals
Hersteller-Nr: 200-301-CF0

Eigenschaften

Anwendung: ELISA, WB
Antikörper-Typ: Monoclonal
Klon: 4G6E11
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human, mouse, rat
Immunogen: 20 amino acid synthetic peptide near the C-terminus of human KLF4.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Anti-KLF4, clone [4G6E11]"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen