Anti-KI67, clone 8K5

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-22027.20 20 µl -

7 - 16 Werktage*

72,00 €
E-AB-22027.60 60 µl -

7 - 16 Werktage*

142,00 €
E-AB-22027.120 120 µl -

7 - 16 Werktage*

238,00 €
E-AB-22027.200 200 µl -

7 - 16 Werktage*

395,00 €
 
Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear... mehr
Produktinformationen "Anti-KI67, clone 8K5"
Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551). Does not contribute to the internal structure of mitotic chromosomes (By similarity). May play a role in chromatin organization (PubMed:24867636). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable). Protein function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551). Does not contribute to the internal structure of mitotic chromosomes. May play a role in chromatin organization (PubMed:24867636). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable). [The UniProt Consortium]
Schlagworte: Anti-Antigen Ki67, Anti-Antigen KI-67, Anti-Proliferation marker protein Ki-67, Anti-Antigen identified by monoclonal antibody Ki-67, KI67 Monoclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-22027

Eigenschaften

Anwendung: IHC (paraffin), IF
Antikörper-Typ: Monoclonal
Klon: 8K5
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human, mouse, rat
Immunogen: Synthetic Peptide
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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