Anti-Ki-67

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ARG66858.100 100 µg - -

6 - 14 Werktage*

624,00 €
 
Protein function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm... mehr
Produktinformationen "Anti-Ki-67"
Protein function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551). Does not contribute to the internal structure of mitotic chromosomes. May play a role in chromatin organization (PubMed:24867636). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable). {ECO:0000250, UniProtKB:E9PVX6, ECO:0000269, PubMed:10878551, ECO:0000269, PubMed:24867636, ECO:0000269, PubMed:27362226}. [The UniProt Consortium]
Schlagworte: Anti-Antigen Ki67 {ECO:0000305}, Anti-Antigen Ki67 {ECO:0000305}, Anti-Antigen KI-67 {ECO:0000305}, Anti-Antigen KI-67 {ECO:0000305}, Anti-Proliferation marker protein Ki-67 {ECO:0000305}, Anti-Proliferation marker protein Ki-67 {ECO:0000305}, Anti-Antige
Hersteller: Arigo Biolaboratories
Hersteller-Nr: ARG66858

Eigenschaften

Anwendung: IHC (paraffin)
Antikörper-Typ: Monoclonal
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human, mouse, rat
Immunogen: Synthetic peptide of Human Ki-67
MW: 359 kD
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: °C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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