Anti-KDELR2, CT (KDELR2, ERD2.2, ER lumen protein retaining receptor 2, ERD2-like protein 1, KDEL en

Anti-KDELR2, CT (KDELR2, ERD2.2, ER lumen protein retaining receptor 2, ERD2-like protein 1, KDEL en
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
037371-HRP.200 200 µl - -

3 - 19 Werktage*

993,00 €
 
Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved... mehr
Produktinformationen "Anti-KDELR2, CT (KDELR2, ERD2.2, ER lumen protein retaining receptor 2, ERD2-like protein 1, KDEL en"
Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR2 was the second member of the family to be identified, and it encodes a protein which is 83% identical to the KDELR1 gene product. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq]. Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Immunohistochemistry: 1:10-50, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Schlagworte: Anti-ELP-1, Anti-KDELR2, Anti-KDEL receptor 2, Anti-ERD2-like protein 1, Anti-ER lumen protein-retaining receptor 2, Anti-KDEL endoplasmic reticulum protein retention receptor 2
Hersteller: United States Biological
Hersteller-Nr: 037371-HRP

Eigenschaften

Anwendung: ELISA, IHC, WB
Antikörper-Typ: Polyclonal
Konjugat: HRP
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: KDELR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182-211 amino acids from the C-terminal region of human KDELR2.
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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