Anti-JHDM1A

Anti-JHDM1A
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
A301-476A-T 10 µl -

3 - 9 Werktage

125,00 €
A301-476A 100 µl (20 µg) -

3 - 9 Werktage

443,00 €
 
Protein function: Histone demethylase that specifically demethylates 'Lys- 36' of histone H3,... mehr
Produktinformationen "Anti-JHDM1A"
Protein function: Histone demethylase that specifically demethylates 'Lys- 36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys- 36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis. [The UniProt Consortium]
Schlagworte: Anti-KDM2A, Anti-CXXC8, EC=1.14.11.27, Anti-F-box protein FBL7, Anti-F-box protein Lilina, Anti-F-box/LRR-repeat protein 11, Anti-Lysine-specific demethylase 2A, Anti-CXXC-type zinc finger protein 8, Anti-[Histone-H3]-lysine-36 demethylase 1A
Hersteller: Bethyl Laboratories
Hersteller-Nr: A301-476A-T

Eigenschaften

Anwendung: WB, IP
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse (Erwartet: Mouse, Rat, Chicken, Turkey, Bovine, Dog, Horse, Rabbit, Guinea Pig_10141, Pig, Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, West Indian Ocean Coelacanth, Tasmanian Devil, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A301-476A-T maps to a region between residue 1112 and 1162 of human JmjC domain-containing histone demethylation protein 1A using the numbering given in entry NP_036440.1 (GeneID 22992).
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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