Anti-IRE1p (Inositol-Requiring Protein 1, IRE1a, IRE1 alpha, Endoplasmic Reticulum-to-Nucleus Signal

Anti-IRE1p (Inositol-Requiring Protein 1, IRE1a, IRE1 alpha, Endoplasmic Reticulum-to-Nucleus Signal
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
I8604-16D.100 100 µl - -

3 - 19 Werktage*

479,00 €
 
IRE1 acts as the sensor of unfolded proteins in the ER that initiates transmittance of the... mehr
Produktinformationen "Anti-IRE1p (Inositol-Requiring Protein 1, IRE1a, IRE1 alpha, Endoplasmic Reticulum-to-Nucleus Signal"
IRE1 acts as the sensor of unfolded proteins in the ER that initiates transmittance of the unfolded protein signal from the ER to the nucleus by splicing XBP1 mRNA converting it into a potent unfolded-protein response transcriptional activator. It is a transmembrane protein that has both serine-threonine kinase and endoribonuclease activities. Null mutants are viable, but IRE1 is essential for viability under stress conditions that cause unfolded proteins to accumulate in the ER. Cellular Localization: Endoplasmic reticulum , Applications: , Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Hersteller: United States Biological
Hersteller-Nr: I8604-16D

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human
Immunogen: A synthetic peptide within the human IRE1 alpha protein (within residues 200-300). Homology: 100% homology with the human and mouse proteins.
Reinheit: Purified by immunoaffinity chromatography.
Format: Affinity Purified

Datenbank Information

Handhabung & Sicherheit

Lagerung: -20°C (-20°C Glycerol)
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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