Anti-IL17C

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-13324.20 20 µl - -

7 - 16 Werktage*

63,00 €
E-AB-13324.60 60 µl - -

7 - 16 Werktage*

119,00 €
E-AB-13324.120 120 µl - -

7 - 16 Werktage*

211,00 €
E-AB-13324.200 200 µl - -

7 - 16 Werktage*

367,00 €
 
The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity... mehr
Produktinformationen "Anti-IL17C"
The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. Protein function: Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases. [The UniProt Consortium]
Schlagworte: Anti-IL17C, Anti-IL-17C, Anti-Cytokine CX2, Anti-Interleukin-17C, IL17C Polyclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-13324

Eigenschaften

Anwendung: WB, IHC, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human
Immunogen: Synthetic peptide of human IL17C
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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