Anti-IL-34 (Human) Capture, Azide Free Clone B-Z34

Specificity: Recognises both natural and recombinant human IL-34, Format: Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free, Working Dilution: The suggested coating concentration range below should be optimised by each laboratory for each application. ELISA: 1-10µg/ml, Storage: Stable at +2-8°C for 12 months. For longer storage freeze aliquots. Protein function: Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. [The UniProt Consortium]