Anti-IL-2

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Interleukin-2, formerly referred to as T-cell growth factor, is a powerfully immunoregulatory lymphokine that is produced by lectin- or antigen-activated T cells. It is produced not only by mature T lymphocytes on stimulation but also constitutively by certain T-cell lymphoma cell lines. The lymphokine interleukin-2 is responsible for autocrine cell cycle progression and regulation of immune responses. Expression in mature thymocytes and T cells has been found to be tightly controlled by monoallelic expression. IL-2 can act as a growth hormone for both B and T lymphocytes. IL-2 is a 17KDa glycoprotein, consisting of 153 amino acids in precursor form and 133 amino acids in mature form. Protein function: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. [The UniProt Consortium]