Anti-IL-17C (Clone: ABM2H52)

Anti-IL-17C (Clone: ABM2H52)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABE-10-4028-100 100 µg -

3 - 11 Werktage*

418,00 €
 
Protein function: Cytokine that plays a crucial role in innate immunity of the epithelium,... mehr
Produktinformationen "Anti-IL-17C (Clone: ABM2H52)"
Protein function: Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases. [The UniProt Consortium]
Schlagworte: Anti-IL17C, Anti-IL-17C, Anti-Cytokine CX2, Anti-Interleukin-17C, Monoclonal Antibody to IL-17C (Clone: ABM2H52)
Hersteller: Abeomics
Hersteller-Nr: 10-4028

Eigenschaften

Anwendung: WB
Antikörper-Typ: Monoclonal
Klon: ABM2H52
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human
Immunogen: Full length recombinant protein of Interleukin-17C was used as the immunogen of this antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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