Anti-IFITM3 [KO Validated]

Anti-IFITM3 [KO Validated]
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
G-CAB13070.100 100 µl -

9 - 20 Werktage*

366,00 €
 
WB 1:500 - 1:2000. Protein function: IFN-induced antiviral protein which disrupts intracellular... mehr
Produktinformationen "Anti-IFITM3 [KO Validated]"
WB 1:500 - 1:2000. Protein function: IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2- mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase). Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pH in phagocytic endosomes thus establishing an antiviral state. [The UniProt Consortium]
Schlagworte: Anti-IFITM3, Anti-DSPA2b, Anti-Dispanin subfamily A member 2b, Anti-Interferon-inducible protein 1-8U, Anti-Interferon-induced transmembrane protein 3, [KO Validated] IFITM3 Polyclonal Antibody (CAB13070)
Hersteller: Assay Genie
Hersteller-Nr: CAB13070

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-133 of human IFITM3 (NP_066362.2).
MW: 15 kD
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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