Anti-IFITM3

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-10850.20 20 µl - -

7 - 16 Werktage*

63,00 €
E-AB-10850.60 60 µl - -

7 - 16 Werktage*

117,00 €
E-AB-10850.120 120 µl - -

7 - 16 Werktage*

208,00 €
E-AB-10850.200 200 µl - -

7 - 16 Werktage*

363,00 €
 
The protein encoded by this gene is an interferon-induced membrane protein that helps confer... mehr
Produktinformationen "Anti-IFITM3"
The protein encoded by this gene is an interferon-induced membrane protein that helps confer immunity to influenza A H1N1 virus, West Nile virus, and dengue virus. Two transcript variants, only one of them protein-coding, have been found for this gene. Another variant encoding an N-terminally truncated isoform has been reported, but the full-length nature of this variant has not been determined. Protein function: IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2- mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase). Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pH in phagocytic endosomes thus establishing an antiviral state. [The UniProt Consortium]
Schlagworte: Anti-DSPA2b, Anti-IFITM3, Anti-Dispanin subfamily A member 2b, Anti-Interferon-inducible protein 1-8U, Anti-Interferon-induced transmembrane protein 3, IFITM3 Polyclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-10850

Eigenschaften

Anwendung: WB, IHC, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human
Immunogen: Recombinant protein of human IFITM3
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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