Anti-ICMT

This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined. Protein function: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues. [The UniProt Consortium]