Anti-HTR1A

Anti-HTR1A
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-12217.20 20 µl - -

7 - 16 Werktage*

63,00 €
E-AB-12217.60 60 µl - -

7 - 16 Werktage*

117,00 €
E-AB-12217.120 120 µl - -

7 - 16 Werktage*

208,00 €
E-AB-12217.200 200 µl - -

7 - 16 Werktage*

363,00 €
 
This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs... mehr
Produktinformationen "Anti-HTR1A"
This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers Protein function: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5- hydroxytryptamine release and in the regulation of dopamine and 5- hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli. [The UniProt Consortium]
Schlagworte: Anti-G-21, Anti-HTR1A, Anti-5-HT1A, Anti-5-HT-1A, Anti-ADRB2RL1, Anti-Serotonin receptor 1A, Anti-5-hydroxytryptamine receptor 1A, HTR1A Polyclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-12217

Eigenschaften

Anwendung: WB, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse, Rat
Immunogen: Synthetic peptide of human HTR1A
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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