Anti-HMG1 (HMGB1, High Mobility Group, HMG Transcription Factor Box1, Amphoterin, Sulfoglucuronyl Ca

Anti-HMG1 (HMGB1, High Mobility Group, HMG Transcription Factor Box1, Amphoterin, Sulfoglucuronyl Ca
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
H6202-03C.100 100 µl - -

3 - 19 Werktage*

546,00 €
 
HMGB1 and HMGB2 are part of the chromatin non-histone high mobility group proteins 1 and 2. These... mehr
Produktinformationen "Anti-HMG1 (HMGB1, High Mobility Group, HMG Transcription Factor Box1, Amphoterin, Sulfoglucuronyl Ca"
HMGB1 and HMGB2 are part of the chromatin non-histone high mobility group proteins 1 and 2. These proteins (containing multiple HMG-boxes) are conserved domains of 80 amino acids which mediate the DNA binding of many proteins. HMG box domains recognize DNA structure. Both HMGB1 and HMGB2 contain an N-terminal HMG box, a central HMG box, and an acidic carboxy terminus. The acidic tails of these proteins contain multiple serine residues which match the phosphorylation consensus sites of casein kinase II, and phosphorylation of this domain appears to be important for proper functioning of these proteins. HMGB1 and HMGB2 have been shown to facilitate the binding of various sequence-specific transcription factors to their respective DNA binding sites. They may also serve as architectural factors that recognize and mediate DNA structural changes that accompany various events such as DNA repair, transcription, and replication. Cellular Localization: Nuclear , Applications: , Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Hersteller: United States Biological
Hersteller-Nr: H6202-03C

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse
Reinheit: Purified by immunoaffinity chromatography.
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C (-20°C Glycerol)
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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