Anti-HIF2A

Anti-HIF2A
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABE-35-1858-50 50 µl -

3 - 11 Werktage*

574,00 €
 
Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA... mehr
Produktinformationen "Anti-HIF2A"
Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation seems to require recruitment of transcriptional coactivators such as CREBPB and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD. Protein function: Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT, heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox regulatory protein APEX1 seems to activate CTAD. [The UniProt Consortium]
Schlagworte: Anti-HLF, Anti-EPAS1, Anti-EPAS-1, Anti-BHLHE73, Anti-bHLHe73, Anti-HIF2-alpha, Anti-HIF-2-alpha, Anti-Member of PAS protein 2, Anti-HIF-1-alpha-like factor, Anti-PAS domain-containing protein 2, Anti-Hypoxia-inducible factor 2-alpha, Polyclonal Antibody
Hersteller: Abeomics
Hersteller-Nr: 35-1858-50

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Peptide sequence around aa.547-551(P-E-E-R-L) derived from HumanHIF2A.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Anti-HIF2A"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen