Anti-H2AFX

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ATA-HPA051647.100 100 µl -

7 - 10 Werktage*

358,00 €
 
Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.... mehr
Produktinformationen "Anti-H2AFX"
Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 85% and to rat: 92%
Schlagworte: Anti-H2a/x, Anti-Histone H2AX, Anti-Histone H2A.X
Hersteller: Atlas Antibodies
Hersteller-Nr: HPA051647

Eigenschaften

Anwendung: ICC, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: PKKTSATVGP KAPSGGKKAT QASQEY (ATA-APrEST89650)

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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