Anti-GITR / TNFRSF18

Anti-GITR / TNFRSF18
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R32938 100 µg - -

3 - 10 Werktage*

755,00 €
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Tumor necrosis factor receptor superfamily... mehr
Produktinformationen "Anti-GITR / TNFRSF18"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. It is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. Protein function: Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. [The UniProt Consortium]
Schlagworte: Anti-AITR, Anti-CD357, Anti-TNFRSF18, Anti-Activation-inducible TNFR family receptor, Anti-Glucocorticoid-induced TNFR-related protein, Anti-Tumor necrosis factor receptor superfamily member 18, GITR Antibody / TNFRSF18
Hersteller: NSJ Bioreagents
Hersteller-Nr: R32938

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: mouse, rat
Immunogen: A recombinant human protein corresponding to amino acids L178-V241 was used as the immunogen for the GITR antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Anti-GITR / TNFRSF18"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen