Anti-Girdin

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
600-401-BK9 100 µg - -

6 - 10 Werktage*

684,00 €
 
Anti-Girdin Antibody was affinity purified from monospecific antiserum by immunoaffinity... mehr
Produktinformationen "Anti-Girdin"
Anti-Girdin Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Girdin from other sources has not been determined. Protein function: Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. Phosphorylation of AKT1/PKB thereby induces the phosphorylation of downstream effectors GSK3 and FOXO1/FKHR, and regulates DNA replication and cell proliferation. Essential for the integrity of the actin cytoskeleton and for cell migration. Required for formation of actin stress fibers and lamellipodia. May be involved in membrane sorting in the early endosome. [The UniProt Consortium]
Schlagworte: Anti-GIV, Anti-APE, Anti-HkRP1, Anti-Girdin, Anti-CCDC88A, Anti-Hook-related protein 1, Anti-Girders of actin filament, Anti-Akt phosphorylation enhancer, Anti-Coiled-coil domain-containing protein 88A, Anti-G alpha-interacting vesicle-associated protein
Hersteller: Rockland Immunochemicals
Hersteller-Nr: 600-401-BK9

Eigenschaften

Anwendung: ELISA, IFM, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
Immunogen: 16 amino acid synthetic peptide from near the C-terminus human Girdin.
Format: Purified

Datenbank Information

UniProt ID : Q3V6T2 | Passende Produkte
Gene ID GeneID 55704 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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