Anti-Geminin / GMNN, clone AEGO-7

Anti-Geminin / GMNN, clone AEGO-7
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-RQ4784 100 µl - -

3 - 10 Werktage*

755,00 €
 
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. Geminin inhibits DNA... mehr
Produktinformationen "Anti-Geminin / GMNN, clone AEGO-7"
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. Geminin inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC) . It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle. [UniProt] Protein function: Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC) (PubMed:9635433, PubMed:14993212, PubMed:20129055, PubMed:24064211). It is degraded during the mitotic phase of the cell cycle (PubMed:9635433, PubMed:14993212, PubMed:24064211). Its destruction at the metaphase- anaphase transition permits replication in the succeeding cell cycle (PubMed:9635433, PubMed:14993212, PubMed:24064211). Inhibits histone acetyltransferase activity of KAT7/HBO1 in a CDT1-dependent manner, inhibiting histone H4 acetylation and DNA replication licensing (PubMed:20129055). Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control (PubMed:22615398). [The UniProt Consortium]
Schlagworte: Anti-GMNN, Anti-Geminin, Geminin Antibody / GMNN
Hersteller: NSJ Bioreagents
Hersteller-Nr: RQ4784

Eigenschaften

Anwendung: WB
Antikörper-Typ: Monoclonal
Klon: AEGO-7
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: A synthetic peptide specific to human Geminin / GMNN
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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