Anti-GAPDH, clone SQab1878

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ARG66330.100 100 µl - -

6 - 14 Werktage*

544,00 €
 
Protein function: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities,... mehr
Produktinformationen "Anti-GAPDH, clone SQab1878"

Protein function: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D- glyceroyl phosphate. Component of the GAIT (gamma interferon- activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. [The UniProt Consortium]

Schlagworte: Anti-GAPD, Anti-GAPDH, Anti-CDABP0047, EC=2.6.99.-, EC=1.2.1.12, Anti-Peptidyl-cysteine S-nitrosylase GAPDH, Anti-Glyceraldehyde-3-phosphate dehydrogenase
Hersteller: Arigo Biolaboratories
Hersteller-Nr: ARG66330

Eigenschaften

Anwendung: FC, ICC, IF, IHC (paraffin), IP, WB
Antikörper-Typ: Monoclonal
Klon: SQab1878
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat, bovine, swine, chicken, Xenopus laevis, zebrafish, african green monkey
Immunogen: Synthetic peptide corresponding to aa. 200-300 of Human GAPDH
MW: 36 kD
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Anti-GAPDH, clone SQab1878"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen