Anti-GAPDH, clone CL3265

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ATA-AMAb91152.25 25 µl -

Fragen Sie uns nach der Lieferzeit

156,00 €
ATA-AMAb91152.100 100 µl -

Fragen Sie uns nach der Lieferzeit

363,00 €
 
Protein function: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities,... mehr
Produktinformationen "Anti-GAPDH, clone CL3265"
Protein function: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3- phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon- activated inhibitor of translation) complex which mediates interferon- gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. [The UniProt Consortium] Validated by genetic and standard strategies. Buffer: The antibodies are delivered in 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 92% and to rat: 94%. Epitope specificity: ERDPSKIKWGDAGAE.
Schlagworte: Anti-GAPD, Anti-GAPDH, Anti-CDABP0047, EC=2.6.99.-, EC=1.2.1.12, Anti-Peptidyl-cysteine S-nitrosylase GAPDH, Anti-Glyceraldehyde-3-phosphate dehydrogenase
Hersteller: Atlas Antibodies
Hersteller-Nr: AMAb91152

Eigenschaften

Anwendung: IHC, WB
Antikörper-Typ: Monoclonal
Klon: CL3265
Konjugat: No
Wirt: Mouse
Reaktivität: Human, Mouse, Rat
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: TVKAENGKLV INGNPITIFQ ERDPSKIKWG DAGAEYVVES TGVFTTMEKA GAHLQGGAKR VIIS (ATA-APrEST81012)

Datenbank Information

KEGG ID : K00134 | Passende Produkte
UniProt ID : P04406 | Passende Produkte
Gene ID : GeneID 2597 | Passende Produkte
Protein Atlas Nr. : ENSG00000111640

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier folgen Informationen zur Produktreferenz. mehr
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Anti-GAPDH, clone CL3265"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen