Anti-FZD2 (PACO03770)

Anti-FZD2 (PACO03770)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
G-PACO03770.50 50 µg - -

9 - 20 Werktage*

231,00 €
 
FZD2 Antibody from Assay Genie with reactivity against Human, Mouse, Rat and for use in ELISA,... mehr
Produktinformationen "Anti-FZD2 (PACO03770)"
FZD2 Antibody from Assay Genie with reactivity against Human, Mouse, Rat and for use in ELISA, WB, IF applications. FZD2 Antibody is Polyclonal and is a IgG isotype antibody from Assay Genie.. Protein function: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes (PubMed:25759469). A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. [The UniProt Consortium]
Schlagworte: Anti-FzE2, Anti-hFz2, Anti-Fz-2, Anti-FZD2, Anti-Frizzled-2
Hersteller: Assay Genie
Hersteller-Nr: PACO03770

Eigenschaften

Anwendung: ELISA, WB, IF
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse, Rat
Immunogen: synthesized peptide derived from the Internal region of human Frizzled-2.
Formel: affinity purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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