Anti-FSH Receptor, clone FSHR/1400

Anti-FSH Receptor, clone FSHR/1400
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-V3322-20UG 20 µg - -

3 - 10 Werktage*

332,00 €
NSJ-V3322-100UG 100 µg - -

3 - 10 Werktage*

752,00 €
 
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Follicle-stimulating... mehr
Produktinformationen "Anti-FSH Receptor, clone FSHR/1400"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Follicle-stimulating hormone receptor (FSHR) is a 695 amino acid G protein coupled receptor. FSH binds to the receptor in a hand-clasp fashion via its alpha and beta subunits. While the alpha subunit of FSH is involved in the binding of FSH to the receptor, the beta subunit stabilizes this interaction. Linkage studies suggest that a missense mutation in the FSHR gene can cause reduced FSH binding affinity and lead to a condition known as hypergonadotropic ovarian dysgenesis (ODG). In males however, this mutation does not appear to have a detrimental affect on fertility. It is believed that a mutation in the FSHR gene is also associated with ovarian hyperstimulation syndrome, a condition characterized by the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells. Protein function: Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Induces cAMP production through the activation of PI3K-AKT and SRC-ERK1/2 signaling pathways. [The UniProt Consortium]
Schlagworte: Anti-LGR1, Anti-FSHR, Anti-FSH-R, Anti-Follitropin receptor, Anti-Follicle-stimulating hormone receptor, FSH Receptor Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: V3322

Eigenschaften

Anwendung: FC, IHC, IF
Antikörper-Typ: Monoclonal
Klon: FSHR/1400
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human
Immunogen: A human recombinant protein was used as the immunogen for this FSHR antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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