Anti-FNTA, ID (Protein Farnesyltransferase/Geranylgeranyltransferase Type-1 Subunit alpha, CAAX Farn

Anti-FNTA, ID (Protein Farnesyltransferase/Geranylgeranyltransferase Type-1 Subunit alpha, CAAX Farn
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
F0019-58X6-HRP.200 200 µl - -

4 - 22 Werktage

696,00 €
 
FNTA, also known as CAAX farnesyltransferase (FTase), attaches a farnesyl group from farnesyl... mehr
Produktinformationen "Anti-FNTA, ID (Protein Farnesyltransferase/Geranylgeranyltransferase Type-1 Subunit alpha, CAAX Farn"
FNTA, also known as CAAX farnesyltransferase (FTase), attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain. This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors. It is likely to be a key component of the signaling pathway which involves p21ras, an important substrate for farnesyltransferase. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Schlagworte: Anti-FNTA, Anti-FTase-alpha, EC=2.5.1.58, EC=2.5.1.59, Anti-GGTase-I-alpha, Anti-CAAX farnesyltransferase subunit alpha, Anti-Ras proteins prenyltransferase subunit alpha, Anti-Type I protein geranyl-geranyltransferase subunit alpha
Hersteller: United States Biological
Hersteller-Nr: F0019-58X6-HRP

Eigenschaften

Anwendung: ELISA, WB
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Human, Mouse
Immunogen: Synthetic peptide selected from the center region of human FNTA (KLH).
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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