Anti-FGFR1, NT (FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR, Fibroblast growth factor receptor 1, Bas

Anti-FGFR1, NT (FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR, Fibroblast growth factor receptor 1, Bas
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
035639.200 200 µl - -

3 - 19 Werktage*

728,00 €
 
FGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is... mehr
Produktinformationen "Anti-FGFR1, NT (FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR, Fibroblast growth factor receptor 1, Bas"
FGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene can lead to Pfeiffer syndrome and Jackson-Weiss syndrome. The genomic organization of the gene is very similar to family members 2-4, encompassing 19 exons that are subject to complex alternative splicing, which allows for structural, tissue expression and ligand affinity variations among the isoforms. Applications: Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, ELISA and Flow Cytometry. Other applications have not been tested. , Recommended Dilutions: Western Blot: 1:1000, Immunohistochemistry (FFPE): 1:50-1:100, Immunofluorescence: 1:50-1:100, Flow Cytometry: 1:10-1:50, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Schlagworte: Anti-BFGFR, Anti-CD331, Anti-N-sam, Anti-FGFR1, Anti-FLT-2, Anti-FGFR-1, Anti-bFGF-R-1, EC=2.7.10.1, Anti-Proto-oncogene c-Fgr, Anti-Fms-like tyrosine kinase 2, Anti-Fibroblast growth factor receptor 1, Anti-Basic fibroblast growth factor receptor 1
Hersteller: United States Biological
Hersteller-Nr: 035639

Eigenschaften

Anwendung: ELISA, FC, IF, IHC, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
Immunogen: FGFR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19~48 amino acids from the N-terminal region of human FGFR1.
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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