Anti-EPS15R, NT (Epidermal Growth Factor Receptor Substrate 15-like 1, Eps15-related Protein, EPS15L

Anti-EPS15R, NT (Epidermal Growth Factor Receptor Substrate 15-like 1, Eps15-related Protein, EPS15L
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E3376-05A-HRP.200 200 µl - -

1 - 19 Werktage

696,00 €
 
Ubiquitin is a 76aa highly conserved eukaryotic polypeptide that selectively marks cellular... mehr
Produktinformationen "Anti-EPS15R, NT (Epidermal Growth Factor Receptor Substrate 15-like 1, Eps15-related Protein, EPS15L"
Ubiquitin is a 76aa highly conserved eukaryotic polypeptide that selectively marks cellular proteins for proteolytic degradation by the 26S proteasome. The process of target selection, covalent attachment and shuttle to the 26S proteasome is a vital means of regulating the concentrations of key regulatory proteins in the cell by limiting their lifespans. Polyubiquitination is a common feature of this modification. Serial steps for modification include the activation of ubiquitin, an ATP-dependent formation of a thioester bond between ubiquitin and the enzyme E1, transfer by transacylation of ubiquitin from E1 to the ubiquitin conjugating enzyme E2, and covalent linkage to the target protein directly by E2 or via E3 ligase enzyme. Deubiquitination enzymes also exist to reverse the marking of protein substrates. Posttranslational tagging by Ub is involved in a multitude of cellular processes, including the cell cycle, cell growth and differentiation, embryogenesis, apoptosis, signal transduction, DNA repair, regulation of transcription and DNA replication, transmembrane transport, stress responses, the immune response, and nervous system functions. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Schlagworte: Anti-EPS15R, Anti-Eps15R, Anti-EPS15L1, Anti-Eps15-related protein, Anti-Epidermal growth factor receptor substrate 15-like 1
Hersteller: United States Biological
Hersteller-Nr: E3376-05A-HRP

Eigenschaften

Anwendung: ELISA, WB
Antikörper-Typ: Polyclonal
Konjugat: HRP
Wirt: Rabbit
Reaktivität: Human
Immunogen: Synthetic peptide selected from the N-terminal region of human EPS15R (KLH).
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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