Anti-eIF3A/eIF3S10

Anti-eIF3A/eIF3S10
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
A302-002A-T 20 µl (2 blots) -

3 - 9 Werktage

125,00 €
A302-002A-M 100 µl (10 blots) -

3 - 9 Werktage

290,00 €
A302-002A 100 µl (100 µg) -

3 - 9 Werktage

430,00 €
 
Protein function: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3)... mehr
Produktinformationen "Anti-eIF3A/eIF3S10"
Protein function: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632, PubMed:11169732). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773, PubMed:27462815). [The UniProt Consortium]
Schlagworte: Anti-eIF3a, Anti-eIF3 p185, Anti-eIF3 p167, Anti-eIF3 p180, Anti-eIF-3-theta, Anti-Eukaryotic translation initiation factor 3 subunit A, Anti-Eukaryotic translation initiation factor 3 subunit 10
Hersteller: Bethyl Laboratories
Hersteller-Nr: A302-002A-T

Eigenschaften

Anwendung: WB, IP
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse (Erwartet: Rat, Zebrafish, X. Tropicalis)
Immunogen: synthetic peptide. The epitope recognized by A302-002A-T maps to a region between residue 1 and 50 of human translation initiation factor 3 subunit A (eukaryotic translation initiation factor 3, subunit 10) using the numbering given in entry NP_003741.1 (GeneID 8661).
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Anti-eIF3A/eIF3S10"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen