Anti-DUSP4 (Dual Specificity Protein Phosphatase 4, Dual Specificity Protein Phosphatase hVH2, HVH2,

Anti-DUSP4 (Dual Specificity Protein Phosphatase 4, Dual Specificity Protein Phosphatase hVH2, HVH2,
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
D9840-08B-FITC.200 200 µl - -

3 - 19 Werktage*

993,00 €
 
DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases... mehr
Produktinformationen "Anti-DUSP4 (Dual Specificity Protein Phosphatase 4, Dual Specificity Protein Phosphatase hVH2, HVH2,"
DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP4 inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Applications: Suitable for use in FLISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: Formalin fixed paraffin embedded., Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Schlagworte: Anti-MKP2, Anti-DUSP4, Anti-MKP-2, EC=3.1.3.16, EC=3.1.3.48, Anti-MAP kinase phosphatase 2, Anti-Dual specificity protein phosphatase 4, Anti-Dual specificity protein phosphatase hVH2, Anti-Mitogen-activated protein kinase phosphatase 2
Hersteller: United States Biological
Hersteller-Nr: D9840-08B-FITC

Eigenschaften

Anwendung: FLISA, IHC
Antikörper-Typ: Polyclonal
Konjugat: FITC
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Synthetic peptide selected from the Center region of human DUSP4 (KLH).
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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