Anti-DUSP1, NT (Dual Specificity Protein Phosphatase 1, CL100, Dual Specificity Protein Phosphatase

Anti-DUSP1, NT (Dual Specificity Protein Phosphatase 1, CL100, Dual Specificity Protein Phosphatase
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
D9840-01A-APC.200 200 µl - -

3 - 19 Werktage*

790,00 €
 
The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and... mehr
Produktinformationen "Anti-DUSP1, NT (Dual Specificity Protein Phosphatase 1, CL100, Dual Specificity Protein Phosphatase"
The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Applications: Suitable for use in FLISA and Western Blot. Other applications not tested. Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze APC conjugates. Light sensitive. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Schlagworte: Anti-CL100, Anti-DUSP1, Anti-MKP-1, EC=3.1.3.16, EC=3.1.3.48, Anti-MAP kinase phosphatase 1, Anti-Protein-tyrosine phosphatase CL100, Anti-Dual specificity protein phosphatase 1, Anti-Dual specificity protein phosphatase hVH1
Hersteller: United States Biological
Hersteller-Nr: D9840-01A-APC

Eigenschaften

Anwendung: FLISA, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human
Immunogen: Synthetic peptide selected from the N-terminal region of human DUSP1 (KLH).
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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