Anti-DUSP1

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-12400.20 20 µl - -

7 - 16 Werktage*

80,00 €
E-AB-12400.60 60 µl - -

7 - 16 Werktage*

156,00 €
E-AB-12400.120 120 µl - -

7 - 16 Werktage*

262,00 €
E-AB-12400.200 200 µl - -

7 - 16 Werktage*

459,00 €
 
The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and... mehr
Produktinformationen "Anti-DUSP1"
The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Protein function: Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle. [The UniProt Consortium]
Schlagworte: Anti-CL100, Anti-DUSP1, Anti-MKP-1, EC=3.1.3.16, EC=3.1.3.48, Anti-MAP kinase phosphatase 1, Anti-Protein-tyrosine phosphatase CL100, Anti-Dual specificity protein phosphatase 1, Anti-Dual specificity protein phosphatase hVH1, DUSP1 Polyclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-12400

Eigenschaften

Anwendung: WB, IHC, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse, Rat
Immunogen: Synthetic peptide of human DUSP1
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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