Anti-Dicer1 (DICER1, DICER, HERNA, KIAA0928, Endoribonuclease Dicer, Helicase with RNase motif)

This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1000, Western Blot: 1:500~2000, Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.