Anti-Cyclin C

Anti-Cyclin C
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-64748.60 60 µl - -

7 - 16 Werktage

119,00 €
E-AB-64748.120 120 µl - -

7 - 16 Werktage

211,00 €
E-AB-64748.200 200 µl - -

7 - 16 Werktage

367,00 €
 
The protein encoded by this gene is a member of the cyclin family of proteins. The encoded... mehr
Produktinformationen "Anti-Cyclin C"
The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene. Protein function: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex. [The UniProt Consortium]
Schlagworte: Anti-CCNC, Anti-hSRB11, Anti-Cyclin-C, Anti-SRB11 homolog, Cyclin C Polyclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-64748-60µL

Eigenschaften

Anwendung: WB, IF
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse, Rat
Immunogen: Recombinant protein of human CCNC

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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