Anti-Cyclin C (CCNC)

Anti-Cyclin C (CCNC)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-F41289-0.08ML 80 µl - -

3 - 10 Werktage*

326,00 €
NSJ-F41289-0.4ML 400 µl - -

3 - 10 Werktage*

702,00 €
 
In 1X PBS, pH 7.4, with 0.09% sodium azide. The protein encoded by this gene is a member of the... mehr
Produktinformationen "Anti-Cyclin C (CCNC)"
In 1X PBS, pH 7.4, with 0.09% sodium azide. The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene. Protein function: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex. [The UniProt Consortium]
Schlagworte: Anti-CCNC, Anti-hSRB11, Anti-Cyclin-C, Anti-SRB11 homolog, Cyclin C Antibody (CCNC)
Hersteller: NSJ Bioreagents
Hersteller-Nr: F41289

Eigenschaften

Anwendung: WB, FC, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this Cyclin C antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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