Anti-cMet (human) [Llama]

Anti-cMet (human) [Llama]
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
QVQ-Q22.250 250 µg - -

3 - 8 Werktage*

383,00 €
 
Type: single domain antibody. Protein function: Receptor tyrosine kinase that transduces signals... mehr
Produktinformationen "Anti-cMet (human) [Llama]"
Type: single domain antibody. Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects. During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation. In adults, participates in wound healing as well as organ regeneration and tissue remodeling. Promotes also differentiation and proliferation of hematopoietic cells. May regulate cortical bone osteogenesis. [The UniProt Consortium]
Schlagworte: Anti-MET, EC=2.7.10.1, Anti-SF receptor, Anti-HGF receptor, Anti-HGF/SF receptor, Anti-Proto-oncogene c-Met, Anti-Scatter factor receptor, Anti-Tyrosine-protein kinase Met, Anti-Hepatocyte growth factor receptor
Hersteller: QVQ
Hersteller-Nr: Q22

Eigenschaften

Anwendung: ELISA, IF, FACS, IP, IHC
Antikörper-Typ: Monoclonal
Klon: Q22 (QME-G2)
Konjugat: No
Wirt: Llama
Reaktivität: Human
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Anti-cMet (human) [Llama]"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen