Anti-CLDN1, clone CL3698

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ATA-AMAb91213.25 25 µl -

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166,00 €
ATA-AMAb91213.100 100 µl -

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370,00 €
 
Protein function: Claudins function as major constituents of the tight junction complexes that... mehr
Produktinformationen "Anti-CLDN1, clone CL3698"
Protein function: Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions (PubMed:23407391). [The UniProt Consortium] Validated by orthogonal and standard strategies. Buffer: The antibodies are delivered in 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 96% and to rat: 96%. Epitope specificity: KTTSYPTPRPYPKPA.
Schlagworte: Anti-CLD1, Anti-CLDN1, Anti-Claudin-1, Anti-Senescence-associated epithelial membrane protein
Hersteller: Atlas Antibodies
Hersteller-Nr: AMAb91213

Eigenschaften

Anwendung: ICC, IHC, WB
Antikörper-Typ: Monoclonal
Klon: CL3698
Konjugat: No
Wirt: Mouse
Reaktivität: Human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KTTSYPTPRP YPKPAPSSGK DYV (ATA-APrEST87501)

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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