Anti-Claudin-1 Recombinant Monoclonal

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
A700-094-T 10 µl (5+ tests) -

2 - 8 Werktage*

172,00 €
A700-094 100 µl (50+ tests) -

2 - 8 Werktage*

655,00 €
 
Protein function: Claudins function as major constituents of the tight junction complexes that... mehr
Produktinformationen "Anti-Claudin-1 Recombinant Monoclonal"
Protein function: Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions (PubMed:23407391). [The UniProt Consortium]
Schlagworte: Anti-CLD1, Anti-CLDN1, Anti-Claudin-1, Anti-Senescence-associated epithelial membrane protein
Hersteller: Bethyl Laboratories
Hersteller-Nr: A700-094

Eigenschaften

Anwendung: WB, IP, IHC, ICC
Antikörper-Typ: Monoclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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