Anti-CENP-F/Mitosin (IHC)

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
IHC-00315-T 10 µl (1 µg) -

2 - 8 Werktage*

164,00 €
IHC-00315 100 µl (10 µg) -

2 - 8 Werktage*

623,00 €
 
Protein function: Required for kinetochore function and chromosome segregation in mitosis.... mehr
Produktinformationen "Anti-CENP-F/Mitosin (IHC)"
Protein function: Required for kinetochore function and chromosome segregation in mitosis. Required for kinetochore localization of dynein, LIS1, NDE1 and NDEL1. Regulates recycling of the plasma membrane by acting as a link between recycling vesicles and the microtubule network though its association with STX4 and SNAP25. Acts as a potential inhibitor of pocket protein-mediated cellular processes during development by regulating the activity of RB proteins during cell division and proliferation. May play a regulatory or permissive role in the normal embryonic cardiomyocyte cell cycle and in promoting continued mitosis in transformed, abnormally dividing neonatal cardiomyocytes. Interaction with RB directs embryonic stem cells toward a cardiac lineage. Involved in the regulation of DNA synthesis and hence cell cycle progression, via its C-terminus. Has a potential role regulating skeletal myogenesis and in cell differentiation in embryogenesis. Involved in dendritic cell regulation of T-cell immunity against chlamydia. [The UniProt Consortium]
Schlagworte: Anti-CENPF, Anti-CENP-F, Anti-Mitosin, Anti-AH antigen, Anti-Centromere protein F, Anti-Kinetochore protein CENPF
Hersteller: Bethyl Laboratories
Hersteller-Nr: IHC-00315

Eigenschaften

Anwendung: IHC, IHC-IF
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human (Erwartet: orangutan, gorilla, chimpanzee)
Immunogen: synthetic peptide. The epitope recognized by IHC-00315 maps to a region between residue 2350 and 2400 of human centromere protein F (Mitosin) using the numbering given in entry AAA82889.1 (GeneID 1063).
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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