Anti-CDKN2B

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-F42340-0.08ML 80 µl - -

3 - 10 Werktage*

250,00 €
NSJ-F42340-0.4ML 400 µl - -

3 - 10 Werktage*

596,00 €
 
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene lies adjacent to the tumor suppressor gene... mehr
Produktinformationen "Anti-CDKN2B"
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. Protein function: Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest. [The UniProt Consortium]
Schlagworte: Anti-MTS2, Anti-MTS-2, Anti-CDKN2B, Anti-p15INK4B, Anti-p14-INK4b, Anti-p15-INK4b, Anti-Multiple tumor suppressor 2, Anti-Cyclin-dependent kinase 4 inhibitor B, CDKN2B Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: F42340

Eigenschaften

Anwendung: IF, FC, WB, IHC, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human
Immunogen: A portion of amino acids 102-130 from the human protein was used as the immunogen for this CDKN2B antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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