Anti-CD49e (CD49 Antigen-like Family Member E, Fibronectin Receptor alpha, FNRA, Integrin alpha-F, I

Anti-CD49e (CD49 Antigen-like Family Member E, Fibronectin Receptor alpha, FNRA, Integrin alpha-F, I
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
C2405-02L1.100 100 µg - -

3 - 19 Werktage*

916,00 €
 
Integrin a5, is a 140-150kD integrin alpha chain that forms dimers with at least five beta chains... mehr
Produktinformationen "Anti-CD49e (CD49 Antigen-like Family Member E, Fibronectin Receptor alpha, FNRA, Integrin alpha-F, I"
Integrin a5, is a 140-150kD integrin alpha chain that forms dimers with at least five beta chains including b1, 3, 5, 6, and 8. It is a 1018aa residue type I membrane protein with a large 962aa extracellular domain (ECD) and a short 32aa cytoplasmic tail. The N-terminal region of Integrin a5, which is important for ligand binding, contains seven FG-GAP (phenylalanyl-glycyl and glycyl-alanyl-prolyl) consensus repeats that fold into a b-propeller domain. Furin cleavage of the Integrin a5 ECD occurs after Gly 889, generating a disulfide-linked, heteromeric subunit Integrin a5 chain. Integrin a5-containing integrins bind multiple ECM molecules, including Vitronectin, Osteopontin, MMP-2, and TSP. The ECD of human Integrin 5 shares 92aa sequence identity with mouse Integrin a5 ECD. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 2ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Schlagworte: Anti-Integrin alpha-5 heavy chain, Anti-Integrin alpha-5 light chain, Anti-CD49 antigen-like family member E, Anti-Fibronectin receptor subunit alpha
Hersteller: United States Biological
Hersteller-Nr: C2405-02L1

Eigenschaften

Anwendung: WB
Antikörper-Typ: Monoclonal
Klon: 11n34
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human
Immunogen: Recombinant corresponding to aa42-995 from human Integrin a5/CD49e expressed in CHO cells (P08648).
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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