Anti-CD4 (human) [Llama]

Anti-CD4 (human) [Llama]
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
QVQ-Q12.250 250 µg - - -

3 - 8 Werktage*

383,00 €
 
Type: single domain antibody. Protein function: Integral membrane glycoprotein that plays an... mehr
Produktinformationen "Anti-CD4 (human) [Llama]"
Type: single domain antibody. Protein function: Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T- helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages. [The UniProt Consortium]
Schlagworte: Anti-CD4, Anti-T-cell surface glycoprotein CD4, Anti-T-cell surface antigen T4/Leu-3
Hersteller: QVQ
Hersteller-Nr: Q12

Eigenschaften

Antikörper-Typ: Monoclonal
Klon: Q12 (10G1)
Konjugat: No
Wirt: Llama
Reaktivität: Human

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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