Anti-CD137 (mouse), clone M4173

Recognizes mouse CD137. Detects a band of about 40kDa by Western blot. Does not cross-react with human CD137. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. CD137 is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 was shown to enhance immune activity to eliminate tumors in mice.