Anti-CD107a (LAMP-1 lysosome-associated membrane protein-1) (Azide Free)

CD107a, otherwise known as LAMP-1 (lysosome-associated membrane protein-1), a 100-120kD type I integral lysosomal membrane glycoprotein is a member of the LAMP family, which transfers between lysosomes, phagosomes and the plasma membrane, and may play a role in lysosomal membrane protection and in lectin-mediated cell adhesion. Studies have linked enhanced CD107a expression with the metastatic potential of some tumor cells, and with , neurones and glial cells surrounding plaques in Alzheimer's patients. CD107a may also serve as a marker of mast cell activation. Applications: Suitable for use in Flow Cytometry. Other applications have not been tested. Recommended Dilutions: Flow Cytometry: 10ul to label 1x10e6 cells in 100ul. , Optimal dilutions to be determined by the researcher. Recommended Secondary Antibodies: I1904-66A: IgG, F(ab')2 (FITC) Pab Rb xMo , Recommended Negative Control: IgG1 Murine Negative Control: Azide Free , Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.