Anti-CCR3 (Chemokine Receptor 3, CC-CCR-3, CKR3)

Anti-CCR3 (Chemokine Receptor 3, CC-CCR-3, CKR3)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
C2099-85B.40 40 µg - -

3 - 19 Werktage*

346,00 €
 
CCR3 is a member of the seven transmembrane G-protein coupled receptor (GPCR) family, and is a... mehr
Produktinformationen "Anti-CCR3 (Chemokine Receptor 3, CC-CCR-3, CKR3)"
CCR3 is a member of the seven transmembrane G-protein coupled receptor (GPCR) family, and is a high affinity chemokine receptor for the chemokines eotaxin-1 (CCL11), eotaxin-2 (CCL24), eotaxin-3 (CCL26) and MCP-4 (CCL13). In addition, it has been reported to bind RANTES, MCP-3 and MCP-4. CCR3 has been shown to exist in blood, brain, lung, bone marrow, kidney, liver, lymph node, placenta, skin, spleen, thymus, thyroid, uterus, and vessel. The agonists for CXCR3 (IP-10, mig, and I-TAC) act as antagonists for CCR3 by competing for the binding of eotaxin to CCR3. CCR3 likely plays an important role in the migration of eosinophils in allergic airway inflammation and asthma. Meanwhile, CCR3 can also serve as a receptor for HIV-1 cell entry. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.05-0.2ug/ml, Immunohistochemistry: 5-10ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Schlagworte: Anti-CCR3, Anti-CKR3, Anti-CD193, Anti-CCR-3, Anti-CMKBR3, Anti-CC-CKR-3, Anti-C-C CKR-3, Anti-Eosinophil eotaxin receptor, Anti-C-C chemokine receptor type 3
Hersteller: United States Biological
Hersteller-Nr: C2099-85B

Eigenschaften

Anwendung: IHC, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human
Immunogen: Synthetic peptide derived from the N-terminal extracellular domain of human CCR3.
Reinheit: Purified by immunoaffinity chromatography.
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C (-20°C Glycerol)
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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