Anti-CBX6

Anti-CBX6
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-13979.20 20 µl -

7 - 16 Werktage*

71,00 €
E-AB-13979.60 60 µl -

7 - 16 Werktage*

143,00 €
E-AB-13979.120 120 µl -

7 - 16 Werktage*

238,00 €
E-AB-13979.200 200 µl -

7 - 16 Werktage*

396,00 €
 
CBX6 (chromobox protein homolog 6) is a 412 amino acid protein that is a component of the... mehr
Produktinformationen "Anti-CBX6"
CBX6 (chromobox protein homolog 6) is a 412 amino acid protein that is a component of the chromatin-associated PcG complex. Through interaction with PcG, CBX6 modifies chromatin and maintains the transcriptionally repressive state of genes. Members of the chromobox domain protein family are characterized by the presence of a 37 amino acid chromobox (CHRromatin Organization MOdifier) domain. This domain plays a mechanistic role in targeting chromodomain proteins to specific regions of the nucleus. Protein function: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed:21282530). PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin (PubMed:18927235). Recruitment to chromatin might occur in an H3K27me3-independent fashion. May have a PRC1-independent function in embryonic stem cells. [The UniProt Consortium]
Schlagworte: Anti-CBX6, Anti-Chromobox protein homolog 6, CBX6 Polyclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-13979

Eigenschaften

Anwendung: WB, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Recombinant protein of human CBX6
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: 4°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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