Anti-Calponin-1, Rabbit Monoclonal (RM262)

Anti-Calponin-1, Rabbit Monoclonal (RM262)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
REV-31-1143-00-R100 100 µl - -

3 - 9 Werktage*

483,00 €
 
Recombinant Antibody. This antibody reacts to human or mouse Calponin-1. Applications: WB, ICC.... mehr
Produktinformationen "Anti-Calponin-1, Rabbit Monoclonal (RM262)"
Recombinant Antibody. This antibody reacts to human or mouse Calponin-1. Applications: WB, ICC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Calponin-1 is a 34 kDa thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It interacts with actin, tropomyosin and calmodulin. Calponin-1 binds actin to promote and sustain polymerization. The binding of calponin to F-actin inhibits the MgATPase activity of smooth muscle myosin. The expression of Calponion-1 is specific to differentiated mature smooth muscle cells, suggesting a role in contractile functions. It is up-regulated in smooth muscle tissues during postnatal development with a higher content in phasic smooth muscle of the digestive tract. Calponin-1 has been found to be useful in differentiating benign sclerosing lesions of the breast from carcinoma. Calponin-1 positivity has also been noted in malignant myoepithelioma and pleomorphic adenoma of salivary gland origin, as well as angiomatoid malignant fibrous histiocytoma.
Schlagworte: Calponin H1, Smooth Muscle
Hersteller: RevMAb Biosciences
Hersteller-Nr: 31-1143-00

Eigenschaften

Anwendung: WB, ICC
Antikörper-Typ: Monoclonal
Klon: RM262
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Format: Purified

Datenbank Information

UniProt ID : P51911 | Passende Produkte
Gene ID GeneID 1264 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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