Anti-BTLA (B and T Lymphocyte Attenuator, CD272)

Anti-BTLA (B and T Lymphocyte Attenuator, CD272)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
B5001-60.100 100 µg - -

3 - 19 Werktage*

901,00 €
 
B and T Lymphocyte Attenuator (BTLA) also known as CD272, is a 70kD type I transmembrane... mehr
Produktinformationen "Anti-BTLA (B and T Lymphocyte Attenuator, CD272)"
B and T Lymphocyte Attenuator (BTLA) also known as CD272, is a 70kD type I transmembrane glycoprotein of the CD28 family of T cell costimulatory molecules. BTLA functions as a coinhibitor on activated T cells and on B cells and dendritic cells. The extracellular domain (ECD) of this Ig superfamily protein contains one V-type Ig-like domain, which interacts with the Herpes virus entry mediator (HVEM/TNFSF14). The amino acid sequence of the ECD of human BTLA shares only 34% identity to that of mouse BTLA. One human BTLA variant lacking the transmembrane sequence has been reported. Applications: Suitable for use in Western Blot and Direct ELISA. Other applications not tested. Recommended Dilutions: Western Blot: 1-2ug/ml. Using a colormetric detection system, the detection limit is ~5ng/lane under non-reducing and reducing conditions., Direct ELISA: 0.5-1ug/ml. The detection limit is ~2ng/well., Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Schlagworte: Anti-BTLA, Anti-CD272, Anti-B- and T-lymphocyte attenuator, Anti-B- and T-lymphocyte-associated protein
Hersteller: United States Biological
Hersteller-Nr: B5001-60

Eigenschaften

Anwendung: ELISA, WB
Antikörper-Typ: Monoclonal
Klon: 7H92
Konjugat: No
Wirt: Rat
Spezies-Reaktivität: human
Immunogen: NS0-derived recombinant human BTLA (aa25-150) Accession # Q7Z6A9
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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