Anti-BLT1 Receptor (Clone 7B1)

The human BLT1 receptor is a G protein-coupled receptor that mediates the proinflammatory effects of leukotriene B4 (LTB4). Northern blotting reveals that the BLT1 receptor is highly expressed in leukocytes, U937 cells, and to a much lower extent in spleen and thymus. Sheep lung membranes have also been identified as a rich source for receptor isolation and purification. A second, low-affinity LTB4 receptor, BLT2, has also been cloned and characterized. Cayman Chemical's BLT1 Receptor Monoclonal Antibody is a useful tool for the detection of human BLT1 by flow cytometry, immunofluorescence, and immunohistochemistry. The antibody does not cross react with the other leukotriene receptors (BLT2, CysLT1, or CysLT2) and does not work for Western blot analysis of BLT1.Synonyms: BLTR1, Leukotriene B4 Receptor 1, LTB4 Receptor 1. Immunogen: HeLa cells transfected with human BLT1. Clone Designation: 7B1. Formulation: (Request formulation change), 200 µg of protein G-purified monoclonal antibody. Storage Buffer: PBS, pH 7.2, with 50% glycerol, 0.1% BSA, and 0.02% sodium azide. Host: Mouse. Isotype: IgG2a. Applications: FC, IF, and IHC of frozen sections. Cross Reactivity: (+) BLT1 receptor, (-) BLT2 receptor, (-) CysLT1 receptor, (-) CysLT2 receptor. UniProt Accession #: Q15722. Origin: Animal/Mouse.