Anti-BimL (BOD, Bcl2l11, BCL2-like 11 Apoptosis Facilitator, Bcl2 Interacting Mediator of Cell Death

Anti-BimL (BOD, Bcl2l11, BCL2-like 11 Apoptosis Facilitator, Bcl2 Interacting Mediator of Cell Death
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
B1090-32C.100 100 µl - -

3 - 19 Werktage*

572,00 €
 
Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or... mehr
Produktinformationen "Anti-BimL (BOD, Bcl2l11, BCL2-like 11 Apoptosis Facilitator, Bcl2 Interacting Mediator of Cell Death"
Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bim/BOD is a group of three splice variants, BimEL, BimL and BimS, with apparent molecular masses of ~23, 16, and 13kD, respectively. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bim or BOD in human, mouse and rat (1,2). Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously , expressed in multiple tissues and cell lines (1,2). Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot:1:1000, Immunohistochemistry:1:50, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Hersteller: United States Biological
Hersteller-Nr: B1090-32C

Eigenschaften

Anwendung: IHC, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Internal central aa of human Bim.
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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