Anti-BIK / BCL2-interacting killer

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R32211 100 µg - -

3 - 10 Werktage

503,00 €
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Bcl-2-interacting killer is a protein that... mehr
Produktinformationen "Anti-BIK / BCL2-interacting killer"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Bcl-2-interacting killer is a protein that in humans is encoded by the BIK gene. This gene is mapped to 22q13.31. The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. Protein function: Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX. [The UniProt Consortium]
Schlagworte: Anti-BP4, Anti-NBK, Anti-BIK, Anti-BIP1, Anti-Apoptosis inducer NBK, Anti-Bcl-2-interacting killer, BIK Antibody / BCL2-interacting killer
Hersteller-Nr: R32211

Eigenschaften

Anwendung: WB, IHC (paraffin), FC
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Human, Mouse, Rat
Immunogen: Amino acids 1-123 of human BIK were used as the immunogen for the BIK antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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